The functionality of glial cells in the basal ganglia are seriously impaired in MSA and Parkinson’s disease.

GCRF and Factor Gimmel induces Glial Cell activation and the secretion of neurotrophic factors. These nourishing factors enhances the survival and activity of neirby dopaminergic neurons.

As a consequence, the endogenous biosynthesis of dopamine is increased.

Striatum areas in the brain often referred to as the basal ganglia, are seriously damaged in MSA-P.

Dopamine concentration