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Nutritional Medicine Research The Neurogenic Diet Fruit and vegetables are well known for their cancer prevention properties. More than 360 epidemiological and clinical studies, undertaken world-wide, have concluded that populations consuming large amounts of fruit and vegetables have a lower predisposition to develop cancer. Glial Cell Regenerative Factor (GCRF) is an extract produced from selected organic fruit and vegetables. Preliminary clinical studies on the use of GCRF have shown an immediate effect in the regression of two forms of brain tumour: Medulloblastoma and Glioblastoma. The sources of GCRF, being purely fruit and vegetables, allow GCRF to penetrate the blood brain barrier easily and provide the basic substances required for Glial Cell DNA repair. Molecular biologists have identified more than 700 anti-tumour and cancer preventive substances present in fruit and vegetables. In conjunction with a diet, rich in the specifically required fruit and vegetables, GCRF actively helps the healing process of glial cells in the brain. Abnormal functionality of glial cells, the source for the biosynthesis of neurotrophins, reduces the self healing capacity of the brain. GCRF molecular components are purely organic substances, present in fruit and vegetables, and therefore not rejected in their passage through the blood brain barrier. Innovative molecules, or large polypeptides, cannot cross the blood brain barrier. For this reason, GDNF, a protein, cannot be used by itself as a brain therapy. With its 211 amino acid chain, it is not able to penetrate brain blood vessels. GCRF, is able instead, to provide the precursors for GDNF biosynthesis in glial cells. These precursors, mainly organic molecules from food sources, are all recognized as essential brain nutrients. Therefore, they easily penetrate the blood brain barrier and are transported into glial cells, where GCRF is broken down into essential amino acids, ions and other molecular components, required to synthesize GDNF. GDNF is then secreted from glial cells into adjacent dopaminergic neurons, mainly, into neurons of the substantia nigra. Increased secretion of GDNF has been reported to induce an essential neuronal trophic effect. [trophic = nourishment Please e-mail us your questions or suggestions to: |